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Posts Tagged ‘differential diagnosis for mdm’

The murmur of Austin flint is has become an immortal cardiac auscultatory sign even in this  era  of hi tech cardiology.  This is our humble tribute  to the  physicians of those time  , who were blessed with  meticulous observatory  and auditory skills .

In the year 1859 , Austin flint  was able to  delineate the hemodynamics  of Aortic regurgitation . , ( 50 years before the invention of ECG  and  X ray ,  125 years before the echocardiography was  discovered   )

It was his  suggestion , in  severe aortic regurgitation , as the blood leaks back in to LV, the regurgitant  jet mechanically interferes with mitral valve opening and hence a functional obstruction to mitral inflow .This generates a mid and late diastolic murmur from the mitral valve which is heard well in the mitral area.

This was confirmed 100 years later as anterior mitral leaflet flutter by  echocardiography in severe AR.

We have since  improved  our  understanding  about the mechanism of  of mitral MDM  in AR

  • It is  also attributable  to the raise in LVEDP and hence  mitral valve  tend to float early  and assume a relatively closed position.(Resultant functional MV narrowing )
  • One more mechanism that could contribute to Austin flint murmur is the diastolic mitral regurgitation that occur in some cases of acute  severe aortic regurgitation .

Ech0cardiograpic correlates

Anterior mitral leaflet flutter is the classical echo correlate of Austin flint murmur.

Differentiation from organic Mitral stenosis

In mitral stenosis following are present .

  • MDM with presystolic accentuation
  • Opening snap
  • Loud S 1

References

Austin flints original article Flint A. On cardiac murmurs. Am J Med Sci. 1862; 44:29-54

http://www.youtube.com/user/NEJMvideo#p/u/29/iOAmqOYVczE

Hear the Austin flint murmur (Link to Texas heart institute podcast )

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