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Posts Tagged ‘acc esc scai guidelines’

Right now, I am sitting at a yet another national conference on Interventional Cardiology. Two very popular cardiologists, from elite institutes of India are debating on a 60-feet long digital dais, with a flashy background comparable to the Macau skyline. Watching it, are about 600 prosperous delegates , brought from various parts of India. The debate is about, whether to use a single stent or upfront two stent strategy for left main bifurcation disease. The arguments were all too familiar, I just couldn’t concentrate.

I am sure every one will agree ,this topic is being debated for nearly two decades. The answer, we got is crystal clear. 90 % of BFL need just provisional single stent. Rest may require two stents upfront. The quality of the procedure matters more than the technique. Not even Imaging matters much. Of course, we are free to choose DK or various other forms of crush as we like. That’s it. May be, It’s time to we close the shutters on the exclusive and glamorous bifurcation clubs and move on. (until a real Innovation in dedicated bi-furcation stent happens)

The following add on was not part of the debate

*Before any BFL PCI, spend a few silent moments, while the patient is being laid on the cath table . Whether the patient is truly symptomatic, whether he could be a candidate for simple medical management or his lesions are complex enough to deserve a CABG.

Final message

Beginning to wonder, is there a fundamental problem with the current mode of knowledge flow and consumption in the field of cardiology. Why do we keep plagiarizing the same old content in the conferences year after year in spite of being fully aware of the futility? This raises a fundamental issue. As we learn more & more, is there a risk of our wisdom curve getting blunted?

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This study was released in NEJM without much fanfare at the fag end of the last century, (rather the millennium) in 1999. Dr. Bertram Pitt and his team scripted this from the Department of Medicine, University of Michigan School of Medicine, Ann Arbor, USA. One can’t expect even in your dreams a study like this would be be done in the future.

This study tested PTCA vs with a single lipid lowering drug in terms of plaque regression. This conclusion is explicitly illustrated here, and the dramatically dissociated Kaplan and Myers would tell the whole story.

Can you name this trial that can withstand any period of time?

One clue : We do prescribe this drug every day and it beats angioplasty. Some of you may have got it right. Yes, It is the AVERT study: Atorvastatin versus revascularization treatment.(Ref 1) that dare to compare PTCA with a humble statin one to one, and we found the winner long long ago. This study also defined the bench mark for dosage of high intensity Atrovastatin at 80mg/per day.

Final message

I am sure, many of the current generation cardiologists may not know about this study and the conclusion might amuse them as well . The truth is , It deserves a 25-year anniversary celebration. Wishes and congratulations to Dr. Bertram Pitt.

Reference

Pitt B, Waters D, Brown WV, van Boven AJ, Schwartz L, Title LM, Eisenberg D, Shurzinske L, McCormick LS. Aggressive lipid-lowering therapy compared with angioplasty in stable coronary artery disease. Atorvastatin versus Revascularization Treatment Investigators. N Engl J Med. 1999 Jul 8;341(2):70-6. doi: 10.1056/NEJM199907083410202. PMID: 10395630.

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