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Cardiac myxoma  is  an  infrequent cause of  stroke in young . LA myxoma is the commonest  tumor  that can partially dislodge to cause a stroke.

It is not necessarily a  tumor emboli that causes the stroke  , super added thrombus is   common in cerebral artery histological  studies. ( In fact , some have advocated successful thrombolysis for myxoma and stroke !)

When do intervene in stroke due to myxoma ?

Image  courtesy: http://www.medicalscale1.com

As soon as cardiac  myxoma is diagnosed by echocardiography  it is customary to call the cardiac surgeons for their  opinion and feasibility of removing the tumor  at the earliest.

Myxomas need not be removed in an emergency surgery even if it has caused a stroke!

What is the optimal timing of cardiac  surgery in patients  with a cardiac cause of stroke ?

  • Stroke is a major vascular  event .Immediate cardiac  surgery is another major vascular  insult .
  • Extra corporeal circulation is known to affect cerebral perfusion  even in normal persons. In  patients with  acute stroke  this   can  have vital impact.
  • Anticoagulants used  peri -operatively  increase the risk of   converting  a simple stroke into hemorrhagic  one.

Hence , it is advisable to wait for 4 weeks after a stroke before removing the myxoma . One can not expect a controlled studyon this issue .  It  is to be  based on collective  experience of many.

Who should decide ?

A cardiologist, a cardiac surgeon and neurologist should  collectively decide along with patient’s input ( or his proxy)

When there is  a dispute in timing of surgery  Neurologists opinion shall prevail over others as the immediate concern is brain function.

Is there any  indication  at all for doing early surgery ?

High risk mobile tumors demand early removal as further strokes can be avoided. Individual discretion and institutional preferences apply.

Reference :

1 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627525/pdf/TOCMJ-2-115.pdf

2.http://asianannals.ctsnetjournals.org/cgi/reprint/8/2/130

3.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064861/pdf/crn0003-0021.pdf

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