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Archive for March 26th, 2009

What are the advantages or disadvantages of having a short or long left main coronary artery ?

Posted in Uncategorized, tagged on March 26, 2009| Leave a Comment »

Left main coronary artery disease is  a  major form of CAD .

left-main-41A long left main by virtue of  it’s surface area   statistically ,  are  more prone for atherosclerosis as it preferentially affect the proximal vessel.A long and tubular leftmain generally give  the LCX branch at right angles(In the above pateint it is 90*).This makes  interventions in Lcx difficult.

A short leftmain or absent leftmain could be a blessing for the simple reason these people have the unique freedom from developing left main disese the dreaded form of  CAD !

Have a look at this angiogram

left-main-31

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Land mark papers in cardiology : Beta blockers in cardiac failure .The power of simple observation far exceeds the synthesised evidence

Posted in cardiology -Therapeutics, cardiology-ethics, Cardiology-Land mark studies, Uncategorized, tagged , , , , , , , , , , on March 26, 2009| Leave a Comment »

Beta blocker use in cardiac failure has come a full circle from a “contraindication to indication”

You don’t need gimmicks of statistics for science to progress. What you require is meticulous observation.

F .Waagstein of    Sweden just did this  with a  study population of seven  patients .

This land mark study , was least significant statistically , but most significant clinically

Today , as on 2009 , if any one submits a manuscript of a study  to a journal  ,  done with seven patients   he or she   will be called as a  fool  !  BMJ  , in 1975 had a courage in not  doing  so  and thus a break through concept was born.

So young scientists , should not  get bothered about sophisticated statistical method.

Science is not about number gimmicks it is about truth and nothing but truth  ! Truths  may  come out from  single digit study or even a single patient study

beta-blocker

To read & download  this land mark article click here

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