Posted in cardiology-Anatomy, Infrequently asked questions in cardiology (iFAQs), tagged pulmonary artery, pulmonary vein on October 6, 2008| Leave a Comment »
Usually in the the vascular system both artery and vein go together .It is an irony in pulmonary circualtion these two never go together .Another paradox is that pulmonary artery carries the most deoxygenated blood and pulmonary vien carries the purest form of blood in the entrie body , probably God has kept them widely seperated as communication between them seriously affect the physiology.
Posted in cardiology-Anatomy, tagged anatomy, cardiac failure, cardiology, collage, drsvenkatesan, fibroblasts, heart, LV mass, myocardium on July 2, 2008| Leave a Comment »
The average human heart which weighs 300 -400 grams . Contrary to the popular perception heart is not purely a muscular organ. In fact myocytes constitutes only 30% of heart mass. Rest formed by
1.Fibroblasts
2.Endothelial cells
3.Purkinje cells
4.Interstitial cells
5.Collagen
6.Fibrous skeleton
7.Extracellualr matrix.
Cardiac failure is not synonymous with myocardial failure .
Many times cardiac failure is due to supporting structure failure like in connective tissue disorders.
Exceesive fibroblast proliferation and resulting in fibrosis of heart.
Cardiac interstitial failure is new emerging clincal entity.
In future individual cell based therapy will aim at replacing specific cells that are defective or depleting.
Dr.S.Venkatesan MD 