Peer review of an article even in major journals never scrutinise the “Aim of a study ” . However big is the journal, they seem to bother only about the authors, materials, methods, and statistical analysis. If only they peer review an article , right from the “Aim of the study” like ,
- Who asks the research questions?
- Who defines the aim of the study ?
- Who decides which drug to be compared with which drug ?
- Who steers the steering commitee of a trial ?
If only , we could answer these questions without bias , pharma industry and their regulators would have , far more better image than what they have now !
A typical example for , the aim of the study to be wrong , is the “ONTARGET’ study on telmisartan.
Here they ( Who ? ) raised an inappropriate question of “Non inferiority” of one drug with other without any valid reason to compare these two drugs that will benefit the man kind !
Dr.S.Venkatesan MD 
Thanks! Really interesting. I wish i could spend my time on writing articles…just have no time for it.
Hi! I was surfing and found your blog post… nice! I love your blog. 🙂 Cheers! Sandra. R.