Catheter based interventions in TOF has caught the imagination of Interventional cardiologists.decades ago. (Quereshi reported first in 1988 Royal Liverpool hospital ) .Somehow it could not develop into a full-fledged modality. The key issue in TOF is, RVOT obstruction is infundibular with some degree of valvular involvement. While the valvular component is amenable for easy correction by balloon, the infundibular stenosis requires some form of cutting or splitting. Embryologically, the malalignment of IVS is the primary mechanism of obstruction. The balloon catheter is will find it difficult to tackle the alignment defect. .Obviously, surgeons can do a comprehensive RVOT reconstruction.
Things are beginning to change. Cutting balloons are available. Various dedicated VSD devices are being developed. Closure of large sub-aortic VSD followed by RVOT dilatation appears challenging task but distinctly possible in the near future.
Few cases of palliative RVOT dilatation with a balloon in critical TOF is been attempted We hope, in the coming decades at least simple forms of TOF are conquered by the interventional cardiologists!
Hardware: A small profile coronary cutting balloon from Boston scientific .
What is in store for the future ?
3D printing of live heart and designer device or deployable patches for the malaligned VSD is possible. Currently, intracardiac ultrasound would assist the procedure.
RVOT reconstruction with RVOT stenting and percutaneous valves (Melody or Right sided TAVR equivalents) is already been done in post-ICR residual obstructions or late RVOT failure
Other References
1.Boucek MM, Webster HE, Orsmond GS, Ruttenberg HD. Balloon pulmonary valvotomy: palliation for cyanotic heart disease. Am Heart J. 1988;115:318-322.
2.Qureschi SA, Kirk CR, Lamb RK, Arnold R, Wilkinson JL. Balloon dilatation of the pulmonary valve in the first year of life in patients with tetralogy of Fallot: a preliminary study. Br Heart J. 1988; 60:232-235.
4.De Geeter P, Weisburd P, Dillenseger P, Willard D. Valvuloplastie pulmonaire percutanée palliative dans les formes néonatales de tétralogie de Fallot. Arch Fr Pediatr. 1989;46:117-119.
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