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Archive for the ‘cardiac radiology’ Category

Epicardial fat is increasingly recognised to be a coronary risk factor.
Methods to measure and quantify epicardial fat has not been standardised.
Nomenclature issues
There is some confusion in the literature regarding  the definition epicardial, pericardial , paracardiac fat etc.
Epicardial fat is the true visceral fat located in proximity with myocardium .Epicardial fat shares the same blood supply as adjacent myocardium and also show  para-crine functions.This is the risky fat that is metabolically active.
Paracardiac fat  is  the fat deposited outside the parietal  pericardium .It is also referred to as  thoracic fat .They carry less risk and behave more like somatic non visceral fat.
Pericardial fat is a loose terminology .Many  use epicardial and pericardial fat interchangibly .It is to be realised , fat either deposit inside the visceral pericardium or outside the parietal pericardium. It almost never deposits  within the pericardial space.

* Currently it is better to use  only two terms .Epicardial fat and  thoracic fat .Other terminology should be avoided.

How to measure and quantify epicardial fat ?
Distribution of fat over heart is not uniform .Though it appears a random distribution there app eras to be a pattern to it .It is largely loaded anterior surface of the heart, over the AV grooves, invariably hugging the coronary arteries and great vessel origins.Fat deposition posterior to heart occurs in gross obesity.
There is no accurate way to quantify it . A rough estimate can be arrived . The following investigations are useful.
  • Echo
  • Multi-slice CT  Scan
  • MRI
Epicardial fat pad thickness by M-Mode /2D  is simplest,  but considered crudest modality to quantify.  .Still , it is a useful screening test. In our experience , if there is distinct anterior fat pad > 5mm it is likely to be significant.
However, epicardial fat volume is ideal method to quantify it.(Read below)

Which part of cardiac cycle it is measured ?

Since epicardial  fat is a compressible structure , in diastole the myocardial mass encroaches the epicardium  any imaging modality the distinction between epicardial and para-cardiac fat  tends to attenuated.

Even MRI images obtained with  diastolic  gating ,  may  not be reliable .End systolic frames are now considered ideal.

(J Am Coll Cardiol. 2011 Oct 4;58(15):1640;Distinction of “fat around the heart”.Kaushik M, Reddy YM.)

What is the normal  epi-cardial  fat volume ?

There is no standard normal.In one large study from  Boston in people  with a BMI between 25-30 the  mean epi-cardial fat volume was 125 cubic cms

normal epicardial fat volume

(*Intrathoraic fat  same as para-cardiac fat located outside parietal pericardium )

How to differentiate fat from pericardial fluid ?

It can be a very difficult issue especially  when you expect both as in hypothyroidism .It needs proper  gain settings and interpretation.

Here is case report of how epicardial fat was mistken for PE even in TEE

Can we measure  the  net mass of  cardiac  fat , does it compress the heart ?

When we say average heart weighs 300 grams it includes fat embedded in it. I don’t think it is possible to measure the fat mass ,but clinically it may be important.Read this .Can-epicardial-fat-constrict-the-heart-an-authentic-yes-from-ulsan-korea ?

Final message

Estimation of epicardial fat volume is largely a research tool.In grossly obese patients it may  have some clinical utility.Increased anterior fat pad in routine 2D echo is an useful  screening test. However, it requires MRI/CT imaging for accurate quantification.

References

how to measure epicardial fat framingham study
2. Marwan J M, Achenbach .S  Cardiovasc Comput Tomogr. .Quantification of epicardial fat by computed tomography: why, when and how?2013 Jan-Feb;7(1):3-10
3. Sarin S, Wenger C, Marwaha A, Clinical significance of epicardial fat measured using cardiac multislice computed tomography. Am J Cardiol. 2008 Sep 15;102(6):767-71.

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Have you ever wondered a given chest x-ray is taken in systole or diastole ?  We should . . .  isn’t ?  Statistically chances of a  X ray to  fall in  diastole is 10-20 % more than systole as the later phase is longer . The peculiarity of cardiac anatomy is that ,  the  profile of the heart alters so little between systole and diastole  .Still the blood is pumped  efficiently into both pulmonary and systemic circulation . The left ventricle shortens by 35%  and ejects 65 % of blood . Similarly RV shortens but with  lesser quantum.

ct ratio in systole and diastole influnce of cardiac cycle on ct ratio

In a simple and elegant study  by Stephen Gammill  in 1970  published in Radiology journal,

he concluded the following about the CT ratio between systole and diastole.

  • 52 %   showed changes of 0.3 cm
  • 41 per cent showed alterations of 0.4 to 0.9 cm,
  • Only  7 per cent  showed a significant  variation of 1.0 to 1.7 cm in transverse cardiac diameter.

(I wonder why any follow up studies on this vital issue is scarce !)

xray chest 002

In spite both ventricles contracting during systole the radiological transverse cardiac diameter is relatively undisturbed ! 

Importance of  Rotary , Twist ,Torsional  and Longitudinal motion

The fact that CT ratio does not alter significantly in most ,  imply the heart has some other  kinetic motion which does not compromise the transverse diameter during systole. They are the rotary , and twist  motion .The relative constancy  of  CT ratio  is a good evidence  for existence for such alternate motions .We have since  confirmed  this  by sophisticated echocardiographic techniques .

Another evidence for rotary motion  recognised in the bed side when the apical impulse hits you in the fingers even as the ventricle is supposed to go away from chest wall during systole . This is  the torsional  movement of  LV  apex  and adjacent inter ventricular septum .

Reference

http://radiology.rsna.org/content/94/1/115.abstract

Coming soon

Inspiratory and expiratory  x ray chest and  the effect on cardiac contours .

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pericardial fluid in plain xray chest xray chest roentgen

How  did the  pericardial  fluid became radio opaque ?

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