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Posts Tagged ‘non inferiority clinical trials’

Of late many drugs are entering the  market  for human  consumption backed up by  Non -Inferiority trials (NIT ) .Few examples.

“The ONTARGET trial: Telmisartan is non-inferior to Ramipril in  New Study Results Published in the New England …”

Feb 20, 2013 – in the New England Journal of Medicine Show Dabigatran Etexilate ... daily was non-inferior to warfarin (p=0.01) in preventing recurrent VTE, …”

What is the logic behind these  Non inferiority trials ?

Why it came into vogue ? 

Do you agree with the concept of NIT ?

I have taken the  privilege  of putting my answer in the title. Believers  of NIT please excuse me.

Reference

Non inferiority drug trial

Non inferiority drug trial 2

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