Aspirin confusion spreads to clopidogrel !
It all started with 75 mg clopidogrel in CURE study and others.
It went up to 150, 300, 600, and in some centres 900 mg.
No body knows how much clopidogrel optimally inhibits the platelet.
Aspirin had the same story three decades ago. It started from 40mg went up to 1200mg
and finally settled at 162mgs.
Why this confusion?
It is because there is no simple platletlet function tests available in bedside.
and also the wide safety margin of this drug.At what level clopidogrel is unsafe
is also not clear !
Answers are expected soon .
Dr.S.Venkatesan MD 
Leave a Reply