Dr.S.Venkatesan MD


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Drug eluting stents bare it all ! and bare metal stents cover it all !

December 14, 2008 7:03 am

                                      One of the important principles of  post PCI care is,   we need  to be very careful  till the metal struts are fully endothelialised . This is of vital importance as improper endothelialisation  is a powerful trigger and nidus for a  imminent thrombosis and  acute coronary syndrome.

stent

It is a billion dollor irony , the much hyped DES does exactly what we don’t want ! and still it’s  usage is  increasing world wide .  The drugs (Anti cancer agents)  which coat the DES   are the villains as it  prevents  the  metal struts  from being endothelialised  and  keep the metal surface  raw and vulnerable , while the  much maligned  bare metal stents allow  this natural endothelialisation  process  without any interruption ! So right now it is mandatory  to administer dual antiplatelet agents  life long( life of the stent !)   for the patients with DES.

 Just look , at the following image of  a stent in vitro at  30 days follow up

des

des-2

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Posted by dr s venkatesan

Categories: Cardiology -Interventional -PCI, cardiology -Therapeutics, Infrequently asked questions in cardiology (iFAQs)

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One Response to “Drug eluting stents bare it all ! and bare metal stents cover it all !”

  1. nice pictures.if BMS scores over DES in all aspects,then why all cardiologists prefer DES as the first line treatment.Why so much confusion among cardiologists at the cost of patients suffering? sir, will we return to an era of POBA again ?Does all new discoveries after several years of research end nowhere?

    By dr. p.k dash on September 15, 2012 at 3:56 pm

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