- Endothelium is the largest vascular organ in the body .
- It is constantly being serviced by both the circulating blood from the luminal side as well as from the abluminal plane.
- The discovery of nitric oxide and endothelin was a breakthrough .
- They are under neural, mechanical and endocrine control .
- Negative emotions like anger and depression has a high correlation with hypertension and cardiac event
- Positive emotions like laughter and happiness is expected to have good vascular tone
This fascinating study from Japan and USA (Texas) published in American journal of cardiology , discusses how a comedy movie possibly releases nitric oxide profusely from our endothelium
Link placed with the courtesy of AJC
http://www.ajconline.org/article/S0002-9149(10)01050-7/abstract
Dr.S.Venkatesan MD 
I fully support your article. You present a very valuable lesson; one that I had to learn the hard way! I’ve heard about a media player that helps to shape your positive emotions, it could be a solution to fight what you call deadly emotions while it plays your favorites music and videos, the site is http://www.emoplayer.com but it’s just by invite I’ve been told that the best way to get it it’s to follow them on Twitter and you may receive and invite…….