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Posts Tagged ‘st depression’

How do you report this ST segment ?

A. Isolated ST depression

B. Isolated T Wave Inversion

C. Combination of both

D.Primarily T wave Inversion ,with secondary ST dragging

Answer: Response C, is logical, but applying some ionic sense to the various repolarisation currents in the left shoulder region of action potential , it is the clash between late phase 2 and the premature phase 3 activity, that deforms the initial limb (forward) of T waves , dragging and effacing the ST segment mimicking ST depression. This we have proposed to call it as ST drag effect by T waves. (ST drag is generally more benign , than ST segement depression that begins at J point.

Clinical significance of such ST segment

Without knowing the symptoms or the reason for which this ECG was taken, we shouldn’t interpret this ECG. In this case, it was taken in a 36-year-old woman, routine health check and who has no specific symptom. This almost rules out an ACS or even a CCS. Firther, the fact that the heart rate is normal rules out demand side ischemia as well. Very likely, it should be LVH or anemia or some other systemic medical conditions. (Rarely, neuro-adrenergic-emotional signals from brainstem can tilt the ST segment like this. (Tansient Tako-subo equivalents)

Next step

However, we can’t leave her alone. She needs an echocardiogram to rule out any subclinical myocardial disease. TMT would seem to be a necessity, but false positivity is very likely.( A flamboyant cardiologist would order a CT angiogram either striaghtaway or a day-care radial angiogram. Nothing wrong with that, as long as the patient insists on reaching the bottom of the truth)

What will you do?

Will sit with the patient for atleast 15 minutes, listen to her daily activity ,past history and look for any subtle symptoms, and then decide. It needs lots of courage (or Ignorance) to leave her without any further Investigation. Echocardiogram is a must. (Have seen a HCM variants like this ).TMT is redunant, if her excercise capacity is excellent.

Final message

One more concept on ST segment can be extrapolated by curious observation of some of the ECGs who present at ER. . It is the secondary ST sagging by primary T wave downward forces. (Pushing ST up is also possibe , as we already know it as ERS pattern )

Postamble.

We know, the S point (Technically J ) in ST segment is well defined , while the end of ST segment is hidden in deep mystery in many clinical situations.Mind you, a flattish ST segment, with absent T wave can be an aboslute normality. Here, you can’t measure either ST segment or even the QT interval.

Reference

1.D’Ascenzi F, Anselmi F, Adami PE, Pelliccia A. Interpretation of T-wave inversion in physiological and pathological conditions: Current state and future perspectives. Clin Cardiol. 2020 Aug;43(8):827-833. doi: 10.1002/clc.23365. Epub 2020 Apr 7. PMID: 32259342; PMCID: PMC7403675.

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The most common ECG dilemmas one encounters is to differentiate between the ST segment depression and T wave inversion due to LVH from that of primary ischemia.

Very often  , the entity is misdiagnosed . The implication can be serious , and adding further complexity is exercise stress testing is alos prone for errors in these group of patients as false negative or positive results are very common due to basline  ST/T changes.So it needs a CAG to confirm or rule out CAD in many .

Still the clinical acumen with the help of ECG can help us to a great extent !

A rough and approximate way to identify primary ischemia is given below.

Though these  humble ECG features may not be specific to diagnose CAD . One  need to remember even a normal coronary angiogram is  not synonymous with normal coronary arteries !

Read this blog on limitations of CAG .

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                                Acute coronary syndrome (ACS) is currently classified as STEMI and NSTEMI.This classification came into vogue  primarily to  triage patients for thrombolysis eligibility , as ST elevation is the  only criteria for thrombolysis.The  earlier term  non q MI  is largely used  to denote the  present day NSTEMI. In the past q  MI was referring to transmural MI non q MI  to non transmural  pathologically.(Of course , now we know  the relationship between q waves and transmurality is not good )

So when can we still use term non q MI ?

These terminologies of STEMI and NSTEMI are made on admission  at the emergency room.  ACS being a dynamic entity these  patients can  have rapidly changing  ST shifts , from depression to elevation and vice versa. Fresh T wave changes can also occur .Q waves  may or may not develop ,  depending upon the damage sustained to the myocardium and the efficacy of thrombolysis / PCI. So it should be emphasised here STEMI,  NSTEMI ,  q  MI ,  non q MI are the  descriptions of the  same group of patients in different time frames. The common mode of  evolution  of  STEMI  is  to q MI and NSTEMI  into non q MI. Cross overs can occur.

 

 

 The problem here is NSTEMI getting converted into STEMI  is quiet common and has no nomenclature issues . But  when   STEMI down grades  into NSTEMI  there is apparent  nomenclature incompatibility .This category of  patients have  no other labelling option other than “A STEMI evolving into non q MI”. Because one can’t label  STEMI  evolving into NSTEMI as  many of  them  will  have a residual ST elevation as well.

What is the final message ?

The term non q MI is still relevant and is used at discharge , in a patient with STEMI when he or she evolves without a q wave .In the setting of unstable angina , NSTEMI has largely replaced  the term  non q MI either on admission or at discharge.

Before I close

                 The important point to remember here  is NSTEMI getting converted into STEMI  is an adverse outcome and  in fact, it is  a complication and the patient should get an immediate  thrombolysis or PCI , while a STEMI getting converted into non Q MI is generally a  major therapeutic success.( Effective salvaging and preventing q waves )

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